Lower Airway Dysbiosis Exacerbates Lung Cancer
نویسندگان
چکیده
Abstract Summary: Accumulating evidence supports the impact of gut microbiota on clinical efficacy cancer immunotherapies against extraintestinal tumors, but it has not yet been addressed whether local commensals could also dictate prognosis patients with cancer. In this issue Cancer Discovery, Tsay and colleagues demonstrate that lower airway may harbor oral turn IL17-mediated inflammatory pathways reprogram host transcription to exacerbate lung progression. See related article by et al., p. 293.
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ژورنال
عنوان ژورنال: Cancer Discovery
سال: 2021
ISSN: ['2159-8290', '2159-8274']
DOI: https://doi.org/10.1158/2159-8290.cd-20-1641